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Publications

Hochberg, L.R., Bacher, D, Jarosiewicz, B, Masse, N.Y., Simeral, J.D., Vogel, J, Haddadin, S., Liu, J., van der Smagt, P., Donoghue, J.P.
Reach and grasp by people with tetraplegia using a neurally controlled robotic arm.
Nature. 2012 May 17; 485 (7398): 372-5.

Simeral, J.D., Kim, S.P., Black, M.J., Donoghue J.P., and Hochberg, L.R.
Neural control of cursor trajectory and click by a human with tetraplegia 1000 days after implant of an intracortical microelectrode array
Journal of Neural Engineering 2011. 8(2) 025027.

Kim, S.P., Simeral, J.D., Hochberg, L.R., Donoghue, J.P., Friehs, G.M., and Black, M.J.
Point-and-click cursor control with an intracortical neural interface system by humans with tetraplegia.
IEEE Trans Neural Sys Rehabil Eng. 2011, Apr; 19(2): 193-203.

Truccolo, W., Donoghue, J.A., Hochberg, L.R., Eskandar, E.N., Madsen, J.R., Anderson, W.S., Brown, E.N., Halgren, E., and Cash, S.S.
Single-neuron dynamics in human focal epilepsy
Nature Neuroscience Volume: 14, Pages: 635–641 Year published: (2011)

Malik, W.Q., Truccolo, W., Brown, E.N., and Hochberg, L.R.
Efficient Decoding With Steady-State Kalman Filter in Neural Interface Systems
IEEE Transaction on Neural Systems and Rehabilitation Engineering. 2011 Feb; 19(1):25-34. Epub 2010 Nov 15. [pdf]

Keller, C.J., Truccolo, W., Gale, J.T., Eskandar, E., Thesen, T., Carlson, C., Devinsky, O., Kuzniecky, R., Doyle, W.K., Madsen J.R., Schomer, D.L., Mehta, A.D., Brown, E.N., Hochberg, L.R., Ulbert, I., Halgren, E., and Cash, S.S.
Heterogeneous neuronal firing patterns during interictal epileptiform discharges in the human cortex
Brain 2010 Apr 17 133: 1668-1681 [pdf]

Zhuang, J., Truccolo, W., Vargas-Irwin, C., and Donoghue, J.P. (2010 Apr 15).
Decoding 3-D Reach and Grasp Kinematics from High-Frequency Local Field Potentials in Primate Primary Motor Cortex.
IEEE Transactions on Biomedical Engineering. [pdf]

Nurmikko, A.V., Donoghue, J.P., Hochberg, L.R., Patterson, W.R., Song, Y.K., Bull, C.W., Borton, D.A., Laiwalla, F., Park, S., Ming, Y., and Aceros, J. (2010 Feb 25)
Listening to Brain Microcircuits for Interfacing With External World—Progress in Wireless Implantable Microelectronic Neuroengineering Devices.
Proc IEEE. 98:3. 375-388. [pdf]

Truccolo, W.
Stochastic models for multivariate neural point processes: collective dynamics and neural decoding.
in Analysis of Parallel Spike Trains (eds. Grün, S. & Rotter, S.), Springer, New York, 2010

Truccolo, W., Hochberg, L.R., and Donoghue, J.P.
Collective dynamics in human and monkey sensorimotor cortex: Predicting single neuron spikes.
Nature Neuroscience 2009 Dec 6 (Epub ahead of print)

Song, Y.K., Borton, D.A., Park, S., Patterson, W.R., Bull, C.W., Laiwalla, F., Mislow, J., Simeral, J.D., Donoghue, J.P., and Nurmikko, A.V.
Active microelectronic neurosensor arrays for implantable brain communication interfaces.
IEEE Trans Neural Syst Rehabil Eng. 2009 Aug;17(4):339-45. Epub 2009 Jun 5. [pdf]

Hatsopoulos, N.G. and Donoghue, J.P.
The Science of Neural Interface Systems.
Annu Rev Neurosci. 2009 Mar 24. [Epub ahead of print]

Kim S.P., Simeral J., Hochberg L.R., Donoghue J.P., and Black M.J.
Neural control of computer cursor velocity by decoding motor cortical spiking activity in humans with tetraplegia.
J. Neural Engin. 2008 (Dec) 5: 455-476

Donoghue, J.P.
Bridging the brain to the world: a perspective on neural interface systems.
Neuron. 2008 Nov 6;60(3):511-21.

Hochberg, L.R.
Turning thought into action.
N.Engl.J.Med. 2008 Sep 11; 359(11): 1175-7

Truccolo, W., Friehs, G.M., Donoghue, J.P., and Hochberg, L.R.
Primary motor cortex tuning to intended movement kinematics in humans with tetraplegia.
J.Neuroscience 2008 Jan 30; 28(5): 1163-78 [supp. text]

Kim, S.P., Simeral, J.D., Hochberg, L.R., Donoghue, J.P., Friehs, G.M., and Black, M.J.
Multi-state decoding of point-and-click control signals from motor cortical activity in a human with tetraplegia
3rd International IEEE-EMBS Conference 2007 May:486-489 [pdf]

Donoghue, J.P., Hochberg, L.R., Nurmikko, A.V., Black, M.J., Simeral, J.D., and Friehs, G.
Neuromotor prosthesis development.
Med Health R I. 2007 Jan ; 90 (1): 12-5

Hochberg, L.R. and Taylor, D.M.
Intuitive prosthetic limb control.
Lancet. 2007 Feb 3; 369 (9559): 345-6

Donoghue, J.P., Nurmikko, A., Black, M., and Hochberg, L.R.
Assistive technology and robotic control using motor cortex ensemble-based neural interface systems in humans with tetraplegia.
J Physiol. 2007 Mar 15; 579 (Pt 3): 603-11

Truccolo, W. and Donoghue, J.P.
Nonparametric modeling of neural point processes via stochastic gradient boosting regression.
Neural Computation. 2007 19 (3): 672-705 [pdf]

Song, Y.K., Patterson, W.R., Bull, C.W., Borton, D.A., Li, Y., Nurmikko, A.V., Simeral, J.D., and Donoghue, J.P.
A brain implantable microsystem with hybrid RF/IR telemetry for advanced neuroengineering applications.
Conf Proc IEEE Eng. Med Biol. Soc. 2007: 445-8

Hochberg, L.R. and Donoghue, J.P.
Sensors for brain-computer interfaces.
IEEE Eng Med Biol Mag. 2006 ; 25 (5): 32-8

Aaron, R.K., Herr, H.M., Ciombor, D.M., Hochberg, L.R., Donoghue, J.P., Briant, C.L., Morgan, J.R., and Ehrlich, M.G.
Horizons in prosthesis development for the restoration of limb function.
J Am Acad Orthop Surg. 2006 Oct ; 14 (10 Suppl): S198-204

Hochberg, L.R., Serruya, M.D., Friehs, G.M., Mukand, J.A., Saleh, M., Caplan, A.H., Branner, A., Chen, D., Penn, R.D., and Donoghue, J.P.
Neuronal ensemble control of prosthetic devices by a human with tetraplegia.
Nature. 2006 Jul 13; 442 (7099): 164-71

Kübler, A., Mushahwar, V.K., Hochberg, L.R., and Donoghue, J.P.
BCI Meeting 2005--workshop on clinical issues and applications.
IEEE Trans Neural Syst Rehabil Eng. 2006 Jun ; 14 (2): 131-4

Truccolo, W., Eden, U.T., Fellows, M.R., Donoghue, J.P., and Brown, E.N.
A Point Process Framework for Relating Neural Spiking Activity to Spiking History, Neural Ensemble and Extrinsic Covariate Effects.
Journal of Neurophysiology, 93, 1074-1089. 2005.

Eden, U.T., Truccolo, W., Fellows, M.R., Donoghue, J.P., and Brown, E.N.
Reconstruction of Hand Movement Trajectories from a Dynamic Ensemble of Spiking Motor Cortical Neurons.
Proceedings of the 26th Annual International Conference of the IEEE EMBS, San Francisco, CA. 2004.

Serruya M., Hatsopoulos N., Fellows M., Paninski L., and Donoghue J.
Robustness of neuroprosthetic decoding algorithms.
Biol Cybern. 2003 Mar;88(3):219-28.

Serruya M.D., Hatsopoulos N.G., Paninski L., Fellows M.R., and Donoghue J.P.
Instant neural control of a movement signal.
Nature. 2002 Mar 14;416(6877):141-2.

Burrow, M., Dugger, J., Humphrey, D.R., Reed, D.J., and Hochberg, L.R.
Cortical control of a robot using a time-delay neural network
International Conference on Rehabilitation Robotics, 1997. [pdf]

Humphrey, D.R. and Hochberg, L.R.
Intracortical Recording Of Brain Activity For Control Of Limb Prostheses
Proceedings of the Rehabilitation Engineering Society of North America, 1995. [pdf]

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Research supported by:

Rehabilitation R&D Service, Department of Veterans Affairs logo National Institutes of Health logo National Institute for Biomedical Imaging and Bioengineering logo The Eunice Kennedy Shriver National Institute of Child Health and Human Development logo National Institute on Deafness and Other Communication Disorders logo National Institute for Neurological Disorders and Stroke logo National Science Foundation logo Defense Advanced Research Projects Agency logo
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